22 days in Italy Itinerary

22 days in Italy Itinerary

Created using Inspirock Italy attractions planner

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Route & dates

22 days in Italy Itinerary

Start: Cairo
Fly:  6​h 45​min
1
Milan
— 2 nights
Drive:  1​h 30​min
2
Argegno
— 2 nights
Drive:  4​h 30​min
3
Venice
— 4 nights
train:  2​h 15​min
4
Florence
— 4 nights
Drive:  4​h 30​min
5
Amalfi
— 4 nights
+2
taxi + subway + train:  2​h 45​min
6
Rome
— 5 nights
Fly:  6​h 45​min
End: Cairo


2
nights
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
On the 1st (Sat), admire the striking features of Galleria Vittorio Emanuele II. Keep things going the next day: pause for some serene contemplation at Duomo di Milano, examine the collection at Castello Sforzesco, and then stroll the grounds of Monumental Cemetery.

To find reviews, where to stay, traveler tips, and tourist information, use the Milan online itinerary maker .

Cairo, Egypt to Milan is an approximately 7-hour flight. You can also drive; or do a combination of car and ferry. The time zone difference moving from Eastern European Time to Central European Time is minus 1 hour. Traveling from Cairo in September, things will get a bit cooler in Milan: highs are around 28°C and lows about 16°C. Finish your sightseeing early on the 3rd (Mon) to allow enough time to travel to Argegno.

Things to do in Milan

Historic Sites Outdoors Museums

Side Trip

Como
Find places to stay Sep 1 — 3:
Highlights from your plan
Duomo di Milano ©
Duomo di Milano
Galleria Vittorio Emanuele II ©
Galleria Vittorio Emanuele II
Castello Sforzesco ©
Castello Sforzesco

2
nights
Argegno

Argegno ©
Argegno is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about 50km north of Milan and about 15km north of Como. On the 4th (Tue), enjoy the sand and surf at Spiaggia di Onno and then tour the water at your own pace with Turati Centro Nautico Lario. On the next day, choose your vessel at AC Boat and then enjoy the sand and surf at Al Puunt-Snack Beach Bar.

For traveler tips, photos, and more tourist information, read our Argegno tour site .

Traveling by car from Milan to Argegno takes 1.5 hours. Expect a daytime high around 28°C in September, and nighttime lows around 16°C. Finish your sightseeing early on the 5th (Wed) so you can travel to Venice.

Things to do in Argegno

Outdoors Tours Beaches

Side Trips

AC Boat, Al Puunt-Snack Beach Bar, Spiaggia di Onno
Find places to stay Sep 3 — 5:
Highlights from your plan
Turati Centro Nautico Lario ©
Turati Centro Nautico Lario
AC Boat ©
AC Boat

4
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Step out of Venice to go to Padua and see Scrovegni Chapel, which is approximately 52 minutes away. There's still lots to do: explore the activities along Canal Grande, take in the local highlights with Walking tours, explore the world behind art at Peggy Guggenheim Collection, and admire the landmark architecture of Doge's Palace.

To find other places to visit, reviews, and more tourist information, refer to the Venice online trip itinerary builder .

You can drive from Argegno to Venice in 3.5 hours. Expect a daytime high around 29°C in September, and nighttime lows around 17°C. Wrap up your sightseeing on the 9th (Sun) to allow time to take a train to Florence.

Things to do in Venice

Historic Sites Museums Tours

Side Trip

Scrovegni Chapel
Find places to stay Sep 5 — 9:
Highlights from your plan
Canal Grande ©
Canal Grande
St. Mark's Square
St. Mark's Square
Basilica di San Marco
Basilica di San Marco

4
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Get out of town with these interesting Florence side-trips: Siena (Piazza del Campo & Siena Cathedral). And it doesn't end there: admire the masterpieces at Uffizi Galleries, take some stellar pictures from Piazzale Michelangelo, take in nature's colorful creations at The Boboli Gardens, and take an in-depth tour of Basilica di Santa Croce.

To find where to stay, ratings, and more tourist information, you can read our Florence tour itinerary planning site .

Take a train from Venice to Florence in 2.5 hours. Alternatively, you can drive; or take a bus. In September, daytime highs in Florence are 30°C, while nighttime lows are 17°C. Finish up your sightseeing early on the 13th (Thu) so you can travel to Amalfi.

Things to do in Florence

Museums Historic Sites Parks

Side Trip

Siena
Find places to stay Sep 9 — 13:
Highlights from your plan
Uffizi Galleries ©
Uffizi Galleries
Galleria dell'Accademia ©
Galleria dell'Accademia
Cathedral of Santa Maria del Fiore ©
Cathedral of Santa Maria del Fiore

4
nights
Amalfi

Known for its impressive hillside cascade of colorful stone buildings down to the Mediterranean shore, Amalfi is the cultural and commercial heart of southern Italy's Amalfi Coast.
Explore Amalfi's surroundings by going to Le Vigne di Raito (in Vietri sul Mare), Fornillo (in Positano) and Parocchia di San Luca Evangelista (in Praiano). Dedicate the 14th (Fri) to wine at some of the top wineries in the area. The adventure continues: delve into the distant past at Gli Scavi Archeologici di Pompei, pause for some serene contemplation at Duomo di Sant'Andrea, contemplate in the serene atmosphere at Duomo di Ravello, and steep yourself in history at Villa Cimbrone Gardens.

To find traveler tips and tourist information, go to the Amalfi trip planner .

Traveling by combination of train, subway, and taxi from Florence to Amalfi takes 4.5 hours. Alternatively, you can drive; or do a combination of flight, train, and bus. Plan for somewhat warmer nights when traveling from Florence in September since evenings lows in Amalfi dip to 24°C. Finish your sightseeing early on the 17th (Mon) so you can travel to Rome.

Things to do in Amalfi

Tours Historic Sites Parks

Side Trips

Ravello, Le Vigne di Raito, Fornillo, Spiaggia di Atrani, Parocchia di San Luca Evangelista
Find places to stay Sep 13 — 17:
Highlights from your plan
Wine Tours & Tastings
Le Vigne di Raito ©
Le Vigne di Raito
Gli Scavi Archeologici di Pompei ©
Gli Scavi Archeologici di Pompei

5
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Rome is known for historic sites, museums, nightlife, shopping, and classes. Your plan includes some of its best attractions: steep yourself in history at St. Peter's Basilica, appreciate the extensive heritage of Piazza Navona, delve into the distant past at Colosseum, and admire the masterpieces at Vatican Museums.

To see more things to do, maps, and more tourist information, go to the Rome day trip planner .

You can do a combination of taxi, subway, and train from Amalfi to Rome in 3 hours. Other options are to drive; or do a combination of bus and train. Traveling from Amalfi in September, plan for a bit cooler nights in Rome, with lows around 18°C. Finish up your sightseeing early on the 22nd (Sat) so you can travel back home.

Things to do in Rome

Historic Sites Museums Tours

Side Trip

Vatican City
Find places to stay Sep 17 — 22:
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
St. Peter's Basilica ©
St. Peter's Basilica

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