16 days in Northwest Italy Itinerary

16 days in Northwest Italy Itinerary

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Route & dates

16 days in Northwest Italy Itinerary

Start: San Francisco
Fly:  17​h 45​min
1
Venice
— 3 nights
2
Florence
— 2 nights
bus:  1​h 15​min
3
Siena
— 3 nights
Drive:  1​h 45​min
4
Assisi
— 2 nights
5
Rome
— 3 nights
Fly:  15​h 45​min
End: San Francisco

3
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Deepen your sense of the past at sights like Piazza San Marco and Doge's Palace. You'll discover tucked-away gems like San Giorgio Maggiore and Piazza dei Signori. Change things up with these side-trips from Venice: Battistero del Duomo (in Padua) and Castello del Catajo (in Battaglia Terme). The adventure continues: take in the architecture and atmosphere at Basilica di San Marco, wander the streets of Cannaregio, admire the landmark architecture of Venetian Arsenal, and take in the spiritual surroundings of Basilica di Santa Maria Gloriosa dei Frari.

To see ratings, traveler tips, more things to do, and tourist information, you can read our Venice trip maker .

San Francisco, USA to Venice is an approximately 18-hour flight. You can also do a combination of train and flight; or do a combination of flight and train. The time zone difference moving from Pacific Standard Time (PST) to Central European Time (CET) is 9 hours. In April in Venice, expect temperatures between 65°F during the day and 49°F at night. Finish up your sightseeing early on the 3rd (Sun) so you can catch the train to Florence.

Things to do in Venice

Historic Sites Museums Nature

Side Trips

Padua, Castello del Catajo
Find places to stay Apr 30 — May 3:
Highlights from your plan
Doge's Palace ©
Doge's Palace
Piazza San Marco ©
Piazza San Marco

2
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Start off your visit on the 4th (Mon): admire the masterpieces at Pitti Palace, appreciate the extensive heritage of Centro Storico, and then see the interesting displays at Academy Of Florence Art Gallery. Here are some ideas for day two: steep yourself in history at Cathedral of Santa Maria del Fiore, admire the landmark architecture of The Baptistery of St. John, then explore the world behind art at Gallerie Degli Uffizi, then admire the striking features of Basilica San Miniato al Monte, and finally take some stellar pictures from Piazzale Michelangelo.

To see photos, where to stay, reviews, and tourist information, refer to the Florence day trip tool .

Traveling by train from Venice to Florence takes 2.5 hours. Alternatively, you can drive; or take a bus. May in Florence sees daily highs of 71°F and lows of 52°F at night. Finish up your sightseeing early on the 6th (Wed) so you can catcht the bus to Siena.

Things to do in Florence

Historic Sites Museums
Find places to stay May 3 — 6:
Highlights from your plan
Centro Storico ©
Centro Storico
Cathedral of Santa Maria del Fiore ©
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi

3
nights
Siena

Siena ©
Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
You'll explore the less-touristy side of things at Torre del Mangia and La Rocca di Staggia. Visit Palazzo Pubblico and Museo Civico and Abazzia di Torri for their historical value. Explore the numerous day-trip ideas around Siena: Volterra (Porta all'Arco & Cathedral of Santa Maria Assunta). There's still lots to do: take in the architecture and atmosphere at Cappella di Piazza, examine the collection at Museo Delle Armature, contemplate in the serene atmosphere at Sinagoga di Siena, and get engrossed in the history at Archivio di Stato.

To see reviews, ratings, and other tourist information, read our Siena tour itinerary planner.

Traveling by bus from Florence to Siena takes 1.5 hours. Alternatively, you can drive; or take a train. In May, plan for daily highs up to 74°F, and evening lows to 53°F. Finish up your sightseeing early on the 9th (Sat) so you can go by car to Assisi.

Things to do in Siena

Historic Sites Museums

Side Trips

Monteriggioni, Volterra, La Rocca di Staggia, Abazzia di Torri
Find places to stay May 6 — 9:
Highlights from your plan
La Rocca di Staggia ©
La Rocca di Staggia
Palazzo Pubblico and Museo Civico ©
Torre del Mangia ©
Torre del Mangia

2
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Kick off your visit on the 9th (Sat): take in the spiritual surroundings of Eremo delle Carceri, appreciate the extensive heritage of Piazza Superiore di San Francesco, then pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, then explore the ancient world of Roman Forum and Archaeological Museum, and finally step into the grandiose world of Palazzo della Corgna - Palazzo Ducale. On your second day here, contemplate in the serene atmosphere at Cripta di San Francesco, take in the spiritual surroundings of Santa Maria delle Rose, then get to know the fascinating history of Centro Storico, then take in the architecture and atmosphere at Chiesa Nuova, and finally admire the landmark architecture of Basilica di Santa Chiara.

To see reviews, where to stay, photos, and tourist information, refer to the Assisi travel planner .

Drive from Siena to Assisi in 2 hours. Alternatively, you can take a bus; or take a train. In May, plan for daily highs up to 72°F, and evening lows to 52°F. Finish your sightseeing early on the 11th (Mon) so you can drive to Pitigliano.

Things to do in Assisi

Historic Sites Museums

Side Trip

Palazzo della Corgna - Palazzo Ducale
Find places to stay May 9 — 11:
Highlights from your plan
Basilica di Santa Chiara ©
Basilica di Santa Chiara
Eremo delle Carceri ©
Eremo delle Carceri

3
nights
Rome

Rome
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Discover out-of-the-way places like Centro Storico Associazione Centro Storico and Church of St. Louis of the French. Your cultural itinerary includes sights like Colosseum and Pantheon. Go for a jaunt from Rome to Tivoli to see Villa d'Este about 48 minutes away. And it doesn't end there: contemplate the long history of St. Peter's Basilica, take in the architecture and atmosphere at Basilica di Santa Maria degli Angeli e dei Martiri, have fun and explore at Welcome to Rome, and appreciate the extensive heritage of Colle Aventino.

To see maps, other places to visit, photos, and tourist information, read Rome trip itinerary builder .

Drive from Assisi to Rome in 2.5 hours. Alternatively, you can take a train; or take a bus. Traveling from Assisi in May, you can expect nighttime temperatures to be somewhat warmer in Rome, with lows of 58°F. Wrap up your sightseeing on the 14th (Thu) to allow time to travel back home.

Things to do in Rome

Historic Sites Museums Parks

Side Trips

Vatican City, Villa d'Este
Find places to stay May 11 — 14:
Highlights from your plan
Vatican Museums
Vatican Museums
St. Peter's Basilica ©
St. Peter's Basilica
Pantheon ©
Pantheon

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